NFL Week 10 2021 Betting Predictions
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NFL Week 10 2021 Betting Predictions

Get ready for Week 10 of the 2021 NFL Season with the best favourite, underdog, over, and under bets on Week 10 of the 2021 NFL Season.

We are heading the second half of the 2021 NFL Season – with 14 games on the schedule. Get ready for NFL betting action from the best sportsbooks with our NFL Week 10 2021 betting predictions.

Best Favourite: Tennessee Titans have a Defence to Carry them While Henry is Out  

To Win the GameSports InteractionSports InteractionTo Win the Game
New Orleans2.371.61Tennessee

When Derrick Henry went down in Week 8, it looked like the Tennessee Titans were in big trouble. However, following one of the biggest wins of the season – the Titans are one of the best teams in the NFL – with or without Derrick Henry.

The defence carried the Titans to an upset win over the Rams on Sunday night. The Rams could not get anything going against the Titans – turning the ball over twice and allowing five sacks. Ryan Tannehill did just enough to keep the Titans on the field for three touchdown scoring drives.

The Titans get the Saints this week – who looked good but not great at times in Week 9. With Jameis Winston and Michael Thomas both out for the season, the Saints need their defence to step up if they are to make the playoffs.

While the defence had played well, they did not have a great showing in Week 9 against the Atlanta Falcons. The unit gave up 6.4 yards per play and allowed the Falcons to score a last-second field goal to win the game.

This game should be close – with Trevor Siemian filling in as a competent backup. However, with the Titans’ defence coming alive and their receiving core getting healthy – they are the better bet on Sunday.

Tennessee Titans To Win the Game
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Best Underdog: Cleveland Browns Looked Like the Best Team in the AFC Last Week

To Win the GameSports InteractionSports InteractionTo Win the Game
Cleveland1.961.86New England

It is hard to deny that the Cleveland Browns are a better team without Odell Beckham Jr. They went on the road in Week 9 and kick the sh*t out of a quality Bengals team. They head to New England as underdogs in Week 10 in a matchup between playoff hopefuls.

The Browns could potentially get Kareem Hunt back for their game this week. With Kareem Hunt paired with Nick Chubb in the backfield, the Browns have the best rushing attack in the NFL.

NFL Week 10 Best Bets

The Patriots are a good team this season that has struggled at home. They are only 1-4 in Foxboro – with the defence allowing at least 120 yards on the ground in three of the four losses.

The Browns’ defence is also starting to gel. Myles Garrett is the frontrunner for Defensive Player of the Year – with 12.5 sacks in nine games. Garrett and company will blitz aggressively against Mac Jones. While Jones has done well in most games in his career against pressure, the few times a team got to him, the Patriots lost.

Cleveland Browns To Win the Game
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*Please note this preview was written before the news on Nick Chubb potentially out was announced. Wait until Saturday to find out if Chubb is playing before betting on this game.

Best Over: Buccaneers Following the Bye Week Should Score Plenty Against Washington

Game TotalSports Interaction
Over 51.51.91
Under 51.51.91

With their bye week in Week 9, the Buccaneers have a chance to get healthy and get their entire offence back for their showdown against the Washington Football team. While we do not yet know for certain if Rob Gronkowski and Antonio Brown are back this week – if they do return, the Bucs offence is arguably the best in the NFL.

In three games with Gronkowski playing at least 50% of snaps – the Bucs are averaging 34.33 points per game. In five games where Antonio Brown suited up, the Bucs are averaging 34.2 points per game.

Washington’s defence this season has been quite disappointing. The unit ranks last in passing yards allowed (286.8 per game), 29th in total yards per game (389.4 per game), and 29th in points per game (28.38 per game).

Washington may be able to score against the Bucs. When Washington hosted Tampa Bay as underdogs in the NFL Playoffs, Taylor Heinicke and Washington managed 507 yards against the Bucs defence in a 31-23 loss. The Bucs have holes in their secondary this season – which is part of the reason five of eight of their games have hit the over.

Game Total Over 51.5
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Best Under: Can We Trust the Kansas City's Offence after Multiple Poor Performances?

Game TotalSports Interaction
Over 52.01.91
Under 52.01.91

What is going on with the Kansas City Chiefs offence? After three years of dominating the NFL, the Chiefs offence is struggling. In their last three games, the Chiefs have combined for 36 points. The last four Chiefs games have all hit the under.

The Raiders offence is also dealing with some issues – as the loss of Henry Ruggs III takes away their ability to stretch the field. We saw the effects in Week 9 – with the Raiders mustering only 96 passing yards.

Best Bets NFL week 10 2021

Just with the issues, both teams are experiencing on offence – we cannot bet on a typical Raiders-Chiefs high-scoring showdown – even if Desean Jackson joining the Raiders is an interesting wrinkle in this game.

Game Total Under 52.0
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Best Online Sportsbooks to Bet on the NFL

Find the best online sportsbooks to bet on the NFL below. New users who join through the links underneath are eligible for a welcome bonus – which you can use to bet on every game in Week 10 of the 2021 NFL Season.